Fluarix Tetra Drug Interactions

Fluarix Tetra can be concomitantly administered with pneumococcal polysaccharide vaccines in subjects aged 50 years and above (see Pharmacology: Pharmacodynamics under Actions).
Fluarix Tetra can be concomitantly administered with adjuvanted herpes zoster vaccine (Shingrix) (see Pharmacology: Pharmacodynamics under Actions).
If Fluarix Tetra is to be given at the same time as another injectable vaccine, the vaccines should always be administered at different injection sites.
The frequency of injection site pain reported in subjects vaccinated concomitantly with inactivated quadrivalent influenza vaccine (Fluarix Tetra) and 23-valent pneumococcal polysaccharide vaccine (PPV23) is similar to that observed with PPV23 alone, and higher compared to Fluarix Tetra alone.
Incidence of fatigue, headache, myalgia and shivering reported in subjects vaccinated concomitantly with Fluarix Tetra and Shingrix is similar to that observed with Shingrix alone, and higher compared to Fluarix Tetra alone.
Following influenza vaccination, false positive results in serology tests using the ELISA method to detect antibodies against HIV1, Hepatitis C and especially HTLV1 have been observed. The Western Blot technique disproves the false-positive ELISA test results. The transient false positive reactions could be due to the IgM response by the vaccine.